Functional adaptive diversity of the Atlantic salmon T-cell receptor gamma locus.

@article{Yazawa2008FunctionalAD,
  title={Functional adaptive diversity of the Atlantic salmon T-cell receptor gamma locus.},
  author={Ryosuke Yazawa and Glenn A. Cooper and Marianne R Beetz-Sargent and Adrienne Robb and Linda McKinnel and William S Davidson and Ben F. Koop},
  journal={Molecular immunology},
  year={2008},
  volume={45 8},
  pages={
          2150-7
        }
}
The Atlantic salmon (Salmo salar) T-cell receptor gamma (TCRgamma) gene has extensive diversity in its capacity for antigen recognition due to the V-J-C gene segments recombinational possibilities, and N-region diversity. This is the first report completely characterizing and annotating a TCRgamma gene locus in teleosts. We identified two different TCRgamma loci in Atlantic salmon. The first locus, TCRgamma 1, spans 260 kbp and contains four tandemly repeated clusters each of which consists of… CONTINUE READING
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