Functional adaptation of cancellous bone in human proximal femur predicted by trabecular surface remodeling simulation toward uniform stress state.

@article{Tsubota2002FunctionalAO,
  title={Functional adaptation of cancellous bone in human proximal femur predicted by trabecular surface remodeling simulation toward uniform stress state.},
  author={Ken-ichi Tsubota and Taiji Adachi and Yoshihiro Tomita},
  journal={Journal of biomechanics},
  year={2002},
  volume={35 12},
  pages={1541-51}
}
Two-dimensional simulation of trabecular surface remodeling was conducted for a human proximal femur to investigate the structural change of cancellous bone toward a uniform stress state. Considering that a local mechanical stimulus plays an important role in cellular activities in bone remodeling, local stress nonuniformity was assumed to drive trabecular structural change to seek a uniform stress state. A large-scale pixel-based finite element model was used to simulate structural changes of… CONTINUE READING

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