Functional activity of serotoninergic and melatoninergic systems expressed in the skin

@article{Slominski2003FunctionalAO,
  title={Functional activity of serotoninergic and melatoninergic systems expressed in the skin},
  author={Andrzej T. Slominski and Alexander V. Pisarchik and Blazej Zbytek and Desmond J. Tobin and S{\"o}bia Kauser and Jacobo Wortsman},
  journal={Journal of Cellular Physiology},
  year={2003},
  volume={196}
}
We tested the expression of genes coding receptors of a cutaneous serotoninergic/melatoninergic system in whole human skin and in normal and pathologic cultured skin cells. Evaluation of serotonin (5HT), melatonin (MT), and melatonin‐related receptors (MRR) showed expression of the isoforms 5HT2B, 5HT7, and MT1 genes in almost all the tested samples. Expression of other isoforms was less prevalent; 5HT2C, MRR, and MT2 were rarely detected. We also found novel isoforms for MT2, MRR, and 5HT2B… 

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