Functional actions of corticosteroids in the hippocampus.

  title={Functional actions of corticosteroids in the hippocampus.},
  author={Marian Jo{\"e}ls},
  journal={European journal of pharmacology},
  volume={583 2-3},
Corticosteroid hormones are released in high amounts after stress. The hormones enter the brain compartment and bind to high affinity mineralocorticoid receptors--particularly enriched in limbic regions--as well as to lower affinity glucocorticoid receptors which are more ubiquitous. Shortly after the stressful event, corticosteroids (in concert with specific monoamines and neuropeptides) have the potential to increase cellular excitability in subfields of the hippocampus, like the CA1 area… CONTINUE READING
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