Functional Roles of the Interaction of APP and Lipoprotein Receptors

  title={Functional Roles of the Interaction of APP and Lipoprotein Receptors},
  author={Theresa Pohlkamp and Catherine R Wasser and Joachim Herz},
  booktitle={Front. Mol. Neurosci.},
The biological fates of the key initiator of Alzheimer's disease (AD), the amyloid precursor protein (APP), and a family of lipoprotein receptors, the low-density lipoprotein (LDL) receptor-related proteins (LRPs) and their molecular roles in the neurodegenerative disease process are inseparably interwoven. Not only does APP bind tightly to the extracellular domains (ECDs) of several members of the LRP group, their intracellular portions are also connected through scaffolds like the one… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS


Publications citing this paper.
Showing 1-10 of 10 extracted citations


Publications referenced by this paper.
Showing 1-10 of 259 references

Similar Papers

Loading similar papers…