Functional Properties of Striatal Fast-Spiking Interneurons

  title={Functional Properties of Striatal Fast-Spiking Interneurons},
  author={Joshua D. Berke},
  booktitle={Front. Syst. Neurosci.},
Striatal fast-spiking interneurons (FSIs) have a major influence over behavioral output, and a deficit in these cells has been observed in dystonia and Tourette syndrome. FSIs receive cortical input, are coupled together by gap junctions, and make perisomatic GABAergic synapses onto many nearby projection neurons. Despite being critical components of striatal microcircuits, until recently little was known about FSI activity in behaving animals. Striatal FSIs are near-continuously active in… CONTINUE READING


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Functional properties of striatal fast-spiking interneurons

  • JD Citation Berke
  • Front. Syst. Neurosci. 5:45
  • 2011

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