Functional Promiscuity of Two Divergent Paralogs of Type III Plant Polyketide Synthases.

@article{Pandith2016FunctionalPO,
  title={Functional Promiscuity of Two Divergent Paralogs of Type III Plant Polyketide Synthases.},
  author={Shahzad A. Pandith and Niha Dhar and Satiander Rana and Wajid Waheed Bhat and Manoj Kushwaha and Ajai Prakash Gupta and Manzoor A. Shah and Ram A Vishwakarma and Surrinder K Lattoo},
  journal={Plant physiology},
  year={2016},
  volume={171 4},
  pages={2599-619}
}
Plants effectively defend themselves against biotic and abiotic stresses by synthesizing diverse secondary metabolites, including health-protective flavonoids. These display incredible chemical diversity and ubiquitous occurrence and confer impeccable biological and agricultural applications. Chalcone synthase (CHS), a type III plant polyketide synthase, is critical for flavonoid biosynthesis. It catalyzes acyl-coenzyme A thioesters to synthesize naringenin chalcone through a polyketidic… CONTINUE READING