Functional Neuroanatomy of Emotion: A Meta-Analysis of Emotion Activation Studies in PET and fMRI

@article{Phan2002FunctionalNO,
  title={Functional Neuroanatomy of Emotion: A Meta-Analysis of Emotion Activation Studies in PET and fMRI},
  author={K. Luan Phan and Tor D. Wager and Stephan F. Taylor and Israel Liberzon},
  journal={NeuroImage},
  year={2002},
  volume={16},
  pages={331-348}
}
Neuroimagingstudies with positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) have begun to describe the functional neuroanatomy of emotion. Taken separately, specific studies vary in task dimensions and in type(s) of emotion studied and are limited by statistical power and sensitivity. By examining findings across studies, we sought to determine if common or segregated patterns of activations exist across various emotional tasks. We reviewed 55 PET and fMRI… 

Figures and Tables from this paper

In search of specificity: functional MRI in the study of emotional experience.
  • A. SchienleAxel Schäfer
  • Psychology
    International journal of psychophysiology : official journal of the International Organization of Psychophysiology
  • 2009
Functional neuroanatomy of emotions: A meta-analysis
TLDR
Novel statistical techniques were applied to the meta-analysis of 106 PET and fMRI studies of human emotion and predictions made by key neuroscientific models demonstrated partial support for asymmetry accounts.
The neural correlates of happiness: A review of PET and fMRI studies using autobiographical recall methods
TLDR
This article reviews eight positron emission tomography and seven functional magnetic resonance imaging studies that have investigated happiness by using autobiographical recall to induce emotion and integrates these findings, discussing important limitations of the extant literature and suggesting new research directions.
A continuous emotional task activates the left amygdala in healthy volunteers: 18FDG PET study
Neuroimaging methods in affective neuroscience: selected methodological issues.
Effect of image analysis software on neurofunctional activation during processing of emotional human faces
Neural Response to Emotional Salience in Schizophrenia
TLDR
It is shown that patients with schizophrenia exhibit impaired neural responses to emotionally salient stimuli in the right ventral striatum (VS), supporting a role for this structure in the pathophysiology of the illness and suggesting a failure to organize cerebral activity at a global level.
Reliability of an fMRI paradigm for emotional processing in a multisite longitudinal study
TLDR
The results support the reliability of blood oxygen level‐dependent signal in emotion processing areas across different sites and scanners and may inform future efforts to increase efficiency and enhance knowledge of rare conditions in the population through multisite neuroimaging paradigms.
...
...

References

SHOWING 1-10 OF 139 REFERENCES
Neuroanatomical correlates of externally and internally generated human emotion.
TLDR
This study identified brain regions that participate in externally and internally generated human emotion, suggesting that these regions participate in aspects of emotion that do not depend on the nature of the emotional stimulus.
Activation of anterior paralimbic structures during guilt-related script-driven imagery
Neuroanatomical correlates of happiness, sadness, and disgust.
TLDR
This study identifies regions of the brain that participate in happiness, sadness, and disgust, regions that distinguish between positive and negative emotions, and regions that depend on both the elicitor and valence of emotion or their interaction.
Imaging Cognition II: An Empirical Review of 275 PET and fMRI Studies
TLDR
Analysis of regional activations across cognitive domains suggested that several brain regions, including the cerebellum, are engaged by a variety of cognitive challenges.
Emotional arousal and activation of the visual cortex: an fMRI analysis.
Functional activity in the visual cortex was assessed using functional magnetic resonance imaging technology while participants viewed a series of pleasant, neutral, or unpleasant pictures. Coronal
The functional neuroanatomy of major depression: an fMRI study using an emotional activation paradigm
TLDR
An fMRI study using an emotional activation paradigm revealed that passive viewing of the emotionally laden film clip produced a significantly greater activation in the left medial prefrontal cortex and in the right cingulate gyrus in depressed patients than in normal control subjects.
Anger in healthy men: a PET study using script-driven imagery
Emotional activation of limbic circuitry in elderly normal subjects in a PET study.
TLDR
Emotional activation in normal elderly subjects was associated with increases in blood flow in limbic and paralimbic brain structures and may be specific to the emotion being elicited but probably involves complex sensory, association, and memory circuitry.
Functional magnetic resonance imaging studies of emotional processing in normal and depressed patients: effects of venlafaxine.
TLDR
Preliminary results from this ongoing study demonstrate the power of using fMRI to study emotional processes in normal and depressed subjects and to examine mechanisms of action of antidepressant drugs.
...
...