Functional Neuroanatomy of Emotion: A Meta-Analysis of Emotion Activation Studies in PET and fMRI

@article{Phan2002FunctionalNO,
  title={Functional Neuroanatomy of Emotion: A Meta-Analysis of Emotion Activation Studies in PET and fMRI},
  author={K. Luan Phan and Tor D. Wager and Stephan F. Taylor and Israel Liberzon},
  journal={NeuroImage},
  year={2002},
  volume={16},
  pages={331-348}
}
Neuroimagingstudies with positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) have begun to describe the functional neuroanatomy of emotion. Taken separately, specific studies vary in task dimensions and in type(s) of emotion studied and are limited by statistical power and sensitivity. By examining findings across studies, we sought to determine if common or segregated patterns of activations exist across various emotional tasks. We reviewed 55 PET and fMRI… Expand
View on Elsevier
psych.colorado.edu
3,192 Citations
Highly Influential Citations
165
Background Citations
1,161
Methods Citations
118
Results Citations
169

3,192 Citations

Citation Type

Citation Type

Functional Neuroimaging Studies of Human Emotions
TLDR
Observations in several regions of interest in limbic and paralimbic brain regions in emotional responding are reviewed, to determine if common or segregated patterns of activations exist in different emotions and across various emotional tasks. Expand
In search of specificity: functional MRI in the study of emotional experience.
  • A. Schienle, Axel Schäfer
  • Psychology, Medicine
  • International journal of psychophysiology : official journal of the International Organization of Psychophysiology
  • 2009
TLDR
The question as to whether recent fMRI studies on primary affective experiences have truly helped to pinpoint emotion-specific areas in the human brain or whether these studies are afflicted with methodological problems which make such inferences difficult is addressed. Expand
Valence, gender, and lateralization of functional brain anatomy in emotion: a meta-analysis of findings from neuroimaging
TLDR
It is found that males showed more lateralization of emotional activity, and females showed more brainstem activation in affective paradigms, providing evidence that lateralization in emotional activity is more complex and region-specific than predicted by previous theories of emotion and the brain. Expand
Functional neuroanatomy of emotions: A meta-analysis
TLDR
Novel statistical techniques were applied to the meta-analysis of 106 PET and fMRI studies of human emotion and predictions made by key neuroscientific models demonstrated partial support for asymmetry accounts. Expand
fMRI of Emotion
Recent brain imaging work has expanded our understanding of the mechanisms of perceptual, cognitive, and motor functions in human subjects, but research into the cerebral control of emotional and… Expand
Transient and sustained BOLD signal time courses affect the detection of emotion-related brain activation in fMRI
TLDR
The results indicate that regions with a transient response profile like the AI can be missed in block designs if analyses do not account for transient responses, which may bias conclusions from empirical reports and meta-analyses towards an underestimation of these regions and their role in emotion and emotion regulation. Expand
The neural correlates of happiness: A review of PET and fMRI studies using autobiographical recall methods
TLDR
This article reviews eight positron emission tomography and seven functional magnetic resonance imaging studies that have investigated happiness by using autobiographical recall to induce emotion and integrates these findings, discussing important limitations of the extant literature and suggesting new research directions. Expand
A continuous emotional task activates the left amygdala in healthy volunteers: 18FDG PET study
TLDR
Left amygdalar activation assessed with FDG PET is revealed, as well as other major emotion recognition-related brain areas during FER tasks. Expand
Neuroimaging methods in affective neuroscience: selected methodological issues.
TLDR
Focusing on functional magnetic resonance imaging (fMRI), this work questions the unjustified application of proportional global signal scaling in emotion research, which can greatly distort statistical findings in key structures implicated in emotional processing and possibly contributing to conflicting results in affective neuroscience fMRI studies. Expand
Effect of image analysis software on neurofunctional activation during processing of emotional human faces
TLDR
A double analysis of an fMRI dataset using emotional faces revealed comparable whole-group brain responses, and it is unclear to what extent the observed neurofunctional response of the brain cortex during emotional processing depends on the fMRI package used in the analysis. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 139 REFERENCES
Neural Correlates of Levels of Emotional Awareness: Evidence of an Interaction between Emotion and Attention in the Anterior Cingulate Cortex
TLDR
This work used positron emission tomography and 15O-water to measure cerebral blood flow in healthy women during film- and recall-induced emotion and correlated CBF changes attributable to emotion with subjects' scores on the Levels of Emotional Awareness Scale (LEAS), a measure of individual differences in the capacity to experience emotion in a differentiated and complex way. Expand
Neuroanatomical correlates of externally and internally generated human emotion.
TLDR
This study identified brain regions that participate in externally and internally generated human emotion, suggesting that these regions participate in aspects of emotion that do not depend on the nature of the emotional stimulus. Expand
The Emotional Modulation of Cognitive Processing: An fMRI Study
TLDR
Results provide evidence that the emotional valence and arousing nature of stimuli used during the performance of an attention-demanding cognitive task are reflected in discernable, quantitative changes in the functional anatomy associated with task performance. Expand
Activation of anterior paralimbic structures during guilt-related script-driven imagery
TLDR
These results, along with those of previous studies, are consistent with the notion that anterior paralimbic regions of the brain mediate negative emotional states in healthy individuals. Expand
Neuroanatomical correlates of happiness, sadness, and disgust.
TLDR
This study identifies regions of the brain that participate in happiness, sadness, and disgust, regions that distinguish between positive and negative emotions, and regions that depend on both the elicitor and valence of emotion or their interaction. Expand
Imaging Cognition II: An Empirical Review of 275 PET and fMRI Studies
TLDR
Analysis of regional activations across cognitive domains suggested that several brain regions, including the cerebellum, are engaged by a variety of cognitive challenges. Expand
Emotional arousal and activation of the visual cortex: an fMRI analysis.
Functional activity in the visual cortex was assessed using functional magnetic resonance imaging technology while participants viewed a series of pleasant, neutral, or unpleasant pictures. Coronal… Expand
Differential limbic–cortical correlates of sadness and anxiety in healthy subjects: implications for affective disorders
TLDR
These findings are interpreted within a model in which sadness and anxiety are represented by segregated corticolimbic pathways, where a major role is played by selective dorsal cortical deactivations during sadness, and ventral cortical deactivateations in anxiety. Expand
The functional neuroanatomy of major depression: an fMRI study using an emotional activation paradigm
AN important issue regarding the neural basis of major depression is whether the functional brain changes associated with the affect disturbance seen in this syndrome are similar to those that… Expand
Anger in healthy men: a PET study using script-driven imagery
TLDR
It is suggested that the subjective experience of anger is associated with rCBF increases in anterior paralimbic regions of the brain, and this study examined the mediating functional neuroanatomy of anger in eight healthy men. Expand
...
1
2
3
4
5
...