Functional Masking of Deprived Eye Responses by Callosal Input during Ocular Dominance Plasticity

@article{Restani2009FunctionalMO,
  title={Functional Masking of Deprived Eye Responses by Callosal Input during Ocular Dominance Plasticity},
  author={Laura Restani and Chiara Cerri and Marta Pietrasanta and Laura Gianfranceschi and Lamberto Maffei and Matteo Caleo},
  journal={Neuron},
  year={2009},
  volume={64},
  pages={707-718}
}
Monocular deprivation (MD) is a well-known paradigm of experience-dependent plasticity in which cortical neurons exhibit a shift of ocular dominance (OD) toward the open eye. The mechanisms underlying this form of plasticity are incompletely understood. Here we demonstrate the involvement of callosal connections in the synaptic modifications occurring during MD. Rats at the peak of the critical period were deprived for 7 days, resulting in the expected OD shift toward the open eye. Acute… CONTINUE READING

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