Functional MRI for anticancer therapy assessment.

  title={Functional MRI for anticancer therapy assessment.},
  author={Anwar R. Padhani},
  journal={European journal of cancer},
  volume={38 16},
Anticancer drug discovery and development are experiencing a paradigm shift from cytotoxic therapies to more selective therapies that target underlying oncogenic abnormalities. Many newer therapies are cytostatic, for which objective tumour shrinkage is an inappropriate response parameter. There is a growing need to develop surrogate endpoints of drug efficacy to speed up the process of finding effective drug combinations for phase III trials. This review focuses on the developing field of… CONTINUE READING


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