Functional MRI changes in the central motor system in myotonic dystrophy type 1.

@article{Caramia2010FunctionalMC,
  title={Functional MRI changes in the central motor system in myotonic dystrophy type 1.},
  author={Francesca Caramia and Caterina Mainero and Francesca Gragnani and Emanuele Tinelli and Marco Fiorelli and Vanessa Ceschin and Patrizia Pantano and Elisabetta Bucci and Veronica Barra and L. Bozzao and Giovanni Antonini},
  journal={Magnetic resonance imaging},
  year={2010},
  volume={28 2},
  pages={226-34}
}
Myotonic dystrophy type 1 (DM1) is a multisystemic disease involving multiple organ systems including central nervous system (CNS) and muscles. Few studies have focused on the central motor system in DM1, pointing to a subclinical abnormality in the CNS. The aim of our study was to investigate patterns of cerebral activation in DM1 during a motor task using functional MRI (fMRI). Fifteen DM1 patients, aged 20 to 59 years, and 15 controls of comparable age were scanned during a self-paced… CONTINUE READING

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Brain Involvement in Myotonic Dystrophy Type 1: A Morphometric and Diffusion Tensor Imaging Study with Neuropsychological Correlation.

Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists • 2017

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