Functional Haplotypes of the hTERT Gene, Leukocyte Telomere Length Shortening, and the Risk of Peripheral Arterial Disease

@inproceedings{Zhang2012FunctionalHO,
  title={Functional Haplotypes of the hTERT Gene, Leukocyte Telomere Length Shortening, and the Risk of Peripheral Arterial Disease},
  author={Weili Zhang and Yu Chen and Xiaomin Yang and Jingyao Fan and Xuenan Mi and Jizheng Wang and Channa Zhang and Frank B Hu and Rutai Hui},
  booktitle={PloS one},
  year={2012}
}
BACKGROUND The development of peripheral arterial disease (PAD) is heterogeneous even in the presence of similar risk factors. Our aim was to determine whether inter-individual differences in leukocyte telomere length contribute to the susceptibility of PAD. METHODS A total of 485 patients with PAD (defined by the ankle-brachial index) and 970 age- and gender-matched controls were recruited from seven rural communities in Henan Province in China. The relative leukocyte telomere length was… CONTINUE READING
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