Functional Genomic and Proteomic Analysis Reveals Disruption of Myelin-Related Genes and Translation in a Mouse Model of Early Life Neglect

@inproceedings{Bordner2011FunctionalGA,
  title={Functional Genomic and Proteomic Analysis Reveals Disruption of Myelin-Related Genes and Translation in a Mouse Model of Early Life Neglect},
  author={Kelly A. Bordner and Elizabeth D. George and Becky C Carlyle and Alvaro Duque and Robert R Kitchen and Tukiet T Lam and Christopher M. Colangelo and Kathryn L. Stone and Thomas Abbott and Shrikant M. Mane and Angus C. Nairn and Arthur A. Simen},
  booktitle={Front. Psychiatry},
  year={2011}
}
  • Kelly A. Bordner, Elizabeth D. George, +9 authors Arthur A. Simen
  • Published in Front. Psychiatry 2011
  • Biology, Medicine
  • Early life neglect is an important public health problem which can lead to lasting psychological dysfunction. Good animal models are necessary to understand the mechanisms responsible for the behavioral and anatomical pathology that results. We recently described a novel model of early life neglect, maternal separation with early weaning (MSEW), that produces behavioral changes in the mouse that persist into adulthood. To begin to understand the mechanism by which MSEW leads to these changes we… CONTINUE READING

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