Functional Fluorescent Ca2+ Indicator Proteins in Transgenic Mice under TET Control

@article{Hasan2004FunctionalFC,
  title={Functional Fluorescent Ca2+ Indicator Proteins in Transgenic Mice under TET Control},
  author={Mazahir T. Hasan and Rainer W. Friedrich and Thomas Euler and Matthew Evan Larkum and Guenter Giese and Matthias Both and Jens Duebel and Jack Waters and Hermann Bujard and Oliver Griesbeck and Roger Tsien and Takeharu Nagai and Atsushi Miyawaki and Winfried Denk},
  journal={PLoS Biology},
  year={2004},
  volume={2},
  pages={11241 - 11246}
}
Genetically encoded fluorescent calcium indicator proteins (FCIPs) are promising tools to study calcium dynamics in many activity-dependent molecular and cellular processes. Great hopes-for the measurement of population activity, in particular-have therefore been placed on calcium indicators derived from the green fluorescent protein and their expression in (selected) neuronal populations. Calcium transients can rise within milliseconds, making them suitable as reporters of fast neuronal… CONTINUE READING