Functional Expression of GABAA Chloride Channels and Benzodiazepine Binding Sites in Baculovirus Infected Insect Cells

Abstract

We have employed the baculovirus expression system for the production of insect cell membranes having GABA/benzo–diazepine binding sites. Three recombinant baculoviruses each harboring a different GABAA receptor cDNA were introduced into insect cells by simultaneous infection. Infected cells expressed GABA responsive Cl− channels and benzodiazepine binding… (More)
DOI: 10.1038/nbt0692-679

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@article{Carter1992FunctionalEO, title={Functional Expression of GABAA Chloride Channels and Benzodiazepine Binding Sites in Baculovirus Infected Insect Cells}, author={Darrick Carter and Doris Thomsen and Wooseok Im and D J Lennon and Doan Tm Ngo and William Gale and Hae Kyung Im and P. H. Seeburg and Melody Smith}, journal={Bio/Technology}, year={1992}, volume={10}, pages={679-681} }