Functional Dyspepsia: Time to Change Clinical Trial Design?

@article{Lacy2010FunctionalDT,
  title={Functional Dyspepsia: Time to Change Clinical Trial Design?},
  author={Brian E Lacy and Nicholas J Talley and Michael Camilleri},
  journal={The American Journal of Gastroenterology},
  year={2010},
  volume={105},
  pages={2525-2529}
}
Introduction Functional dyspepsia (FD) is a highly prevalent disorder, accounting for 5% of primary-care visits and imposing an economic burden of at least $1 billion per year to the US health-care system (1–4). FD is currently defined by Rome III criteria— symptoms of postprandial fullness, early satiety, or epigastric burning without any evidence of a structural disorder thought to explain symptom expression. The symptoms of FD are nonspecific, however, which makes the diagnosis of FD… CONTINUE READING