Functional Diversification of Paralogous Transcription Factors via Divergence in DNA Binding Site Motif and in Expression

@article{Singh2008FunctionalDO,
  title={Functional Diversification of Paralogous Transcription Factors via Divergence in DNA Binding Site Motif and in Expression},
  author={Larry N. Singh and Sridhar Hannenhalli},
  journal={PLoS ONE},
  year={2008},
  volume={3},
  pages={reviews1012 - 1155}
}
BACKGROUND Gene duplication is a major driver of evolutionary innovation as it allows for an organism to elaborate its existing biological functions via specialization or diversification of initially redundant gene paralogs. Gene function can diversify in several ways. Transcription factor gene paralogs in particular, can diversify either by changes in… CONTINUE READING