Functional Cross Talk between CXCR4 and PDGFR on Glioblastoma Cells Is Essential for Migration


Glioblastoma (GBM) is the most common and aggressive form of brain tumor, characterized by high migratory behavior and infiltration in brain parenchyma which render classic therapeutic approach ineffective. The migratory behaviour of GBM cells could be conditioned by a number of tissue- and glioma-derived cytokines and growth factors. Although the pro… (More)
DOI: 10.1371/journal.pone.0073426


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