Functional Characteristics of ES Cell–derived Cardiac Precursor Cells Identified by Tissue-specific Expression of the Green Fluorescent Protein

@article{Kolossov1998FunctionalCO,
  title={Functional Characteristics of ES Cell–derived Cardiac Precursor Cells Identified by Tissue-specific Expression of the Green Fluorescent Protein },
  author={Eugen Kolossov and B. K. Fleischmann and Qiumei Liu and Wilhelm Bloch and S. Viatchenko-Karpinski and Oliver Manzke and G. J. Ji and Heribert Bohlen and Klaus Addicks and J{\"u}rgen Hescheler},
  journal={The Journal of Cell Biology},
  year={1998},
  volume={143},
  pages={2045 - 2056}
}
In contrast to terminally differentiated cardiomyocytes, relatively little is known about the characteristics of mammalian cardiac cells before the initiation of spontaneous contractions (precursor cells). Functional studies on these cells have so far been impossible because murine embryos of the corresponding stage are very small, and cardiac precursor cells cannot be identified because of the lack of cross striation and spontaneous contractions. In the present study, we have used the murine… CONTINUE READING