Functional Cell Types in Taste Buds Have Distinct Longevities

@inproceedings{PereaMartinez2013FunctionalCT,
  title={Functional Cell Types in Taste Buds Have Distinct Longevities},
  author={Isabel Perea-Martinez and Takatoshi Nagai and Nirupa Chaudhari},
  booktitle={PloS one},
  year={2013}
}
Taste buds are clusters of polarized sensory cells embedded in stratified oral epithelium. In adult mammals, taste buds turn over continuously and are replenished through the birth of new cells in the basal layer of the surrounding non-sensory epithelium. The half-life of cells in mammalian taste buds has been estimated as 8-12 days on average. Yet, earlier studies did not address whether the now well-defined functional taste bud cell types all exhibit the same lifetime. We employed a recently… CONTINUE READING

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 52 CITATIONS, ESTIMATED 40% COVERAGE

Insulin Is Transcribed and Translated in Mammalian Taste Bud Cells.

VIEW 9 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Genetic Lineage Tracing in Taste Tissues Using Sox2-CreERT2 Strain.

  • Chemical senses
  • 2017
VIEW 6 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

Taste bud homeostasis in health, disease, and aging.

  • Chemical senses
  • 2014
VIEW 12 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Progress and renewal in gustation: new insights into taste bud development.

  • Development
  • 2015
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Sonic hedgehog-expressing basal cells are general post-mitotic precursors of functional taste receptor cells.

  • Developmental dynamics : an official publication of the American Association of Anatomists
  • 2014
VIEW 6 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2013
2019

CITATION STATISTICS

  • 8 Highly Influenced Citations

  • Averaged 8 Citations per year over the last 3 years

References

Publications referenced by this paper.
SHOWING 1-10 OF 40 REFERENCES

RENEWAL OF CELLS WITHIN TASTE BUDS

  • The Journal of cell biology
  • 1965
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Only glial-like and receptor cells of mouse taste buds are derived from keratin 14-expressing basal epithelial cells

G Dvoryanchikov, I Perea-Martinez, N Chaudhari
  • Chem Senses
  • 2012
VIEW 1 EXCERPT

The cell biology of taste

  • The Journal of cell biology
  • 2010
VIEW 2 EXCERPTS