Functional Brain Connectivity Using fMRI in Aging and Alzheimer’s Disease

@article{Dennis2014FunctionalBC,
  title={Functional Brain Connectivity Using fMRI in Aging and Alzheimer’s Disease},
  author={Emily L. Dennis and Paul M. Thompson},
  journal={Neuropsychology Review},
  year={2014},
  volume={24},
  pages={49-62}
}
Normal aging and Alzheimer’s disease (AD) cause profound changes in the brain’s structure and function. AD in particular is accompanied by widespread cortical neuronal loss, and loss of connections between brain systems. This degeneration of neural pathways disrupts the functional coherence of brain activation. Recent innovations in brain imaging have detected characteristic disruptions in functional networks. Here we review studies examining changes in functional connectivity, measured through… CONTINUE READING