Functional Annotation of the Ophiostoma novo-ulmi Genome: Insights into the Phytopathogenicity of the Fungal Agent of Dutch Elm Disease

  title={Functional Annotation of the Ophiostoma novo-ulmi Genome: Insights into the Phytopathogenicity of the Fungal Agent of Dutch Elm Disease},
  author={Andr{\'e} M. Comeau and Jos{\'e}e Dufour and Guillaume F. Bouvet and Volker Jacobi and Martha Nigg and Bernard Henrissat and J{\'e}r{\^o}me Laroche and Roger C. Levesque and Louis Bernier},
  journal={Genome Biology and Evolution},
  pages={410 - 430}
The ascomycete fungus Ophiostoma novo-ulmi is responsible for the pandemic of Dutch elm disease that has been ravaging Europe and North America for 50 years. We proceeded to annotate the genome of the O. novo-ulmi strain H327 that was sequenced in 2012. The 31.784-Mb nuclear genome (50.1% GC) is organized into 8 chromosomes containing a total of 8,640 protein-coding genes that we validated with RNA sequencing analysis. Approximately 53% of these genes have their closest match to Grosmannia… 

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