Functional Analysis of the Campylobacter jejuni cj0183 and cj0588 Genes

  title={Functional Analysis of the Campylobacter jejuni cj0183 and cj0588 Genes},
  author={Agnieszka Sałamaszyńska-Guz and Danuta Klimuszko},
  journal={Current Microbiology},
The cj0183 and cj0588 genes identified in the Campylobacter jejuni NCTC 11168 genome encode proteins with amino acid sequences predicted to be homologous to other bacterial hemolysins. The Cj0183 protein exhibits homology to Brachyspira hyodysenteriae TlyC protein, whereas the cj0588 gene product is homologous to TlyA proteins Brachyspira hyodysenteriae, Helicobacter pylori, and Mycobacterium tuberculosis, which play a crucial role in bacterial virulence. The aim of our work was to examine the… CONTINUE READING


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Two-toxins related genes of C. jejuni have a role in colonisation of the chickens

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