Functional Analysis of Mononuclear Cells Infiltrating into Tumors: Establishment of T Cell Hybridomas Exhibiting Distinct Interacting Abilities with Endothelial Cells and Extracellular Matrix Components

Abstract

We have established eleven T cell hybridoma cell lines to investigate mechanisms controlling interaction of T lymphocytes with endothelial cells as well as extracellular matrix (ECM) proteins at the clonal level. T cell hybridomas were characterized and subdivided into four groups on the basis of their interaction behavior with high endothelial venules (HEV… (More)

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