Functional, signalling and transcriptional differences of three distinct type I IFNs in a perciform fish, the mandarin fish Siniperca chuatsi

@article{Laghari2018FunctionalSA,
  title={Functional, signalling and transcriptional differences of three distinct type I IFNs in a perciform fish, the mandarin fish Siniperca chuatsi},
  author={Zubair Ahmed Laghari and Shannan Chen and Li Li and Bei Huang and Zhen Gan and Ying Zhou and Hui Jun Huo and Jing Hou and Pin Nie},
  journal={Developmental and Comparative Immunology},
  year={2018},
  volume={84},
  pages={94–108}
}
&NA; Teleost fish are unique in having type I and type II interferons (IFNs) only, and the type I IFNs are classified into Group one and Group two based on the presence of two or four cysteines respectively, and are further classified into seven subgroups. In the present study, three distinct type I IFNs, IFNc, IFNd and IFNh, have been identified in the genome sequences of a perciform fish, the mandarin fish Siniperca chuatsi. These IFNs are induced following the stimulation of Polyinosinic… Expand
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TLDR
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The variation in the composition of type I and type II IFNs as well as in their receptors in some cyprinid and salmonid fish has also been reviewed and it is suggested that future perspectives for the research on type II and type I IFNs in fish are outlined from a comparative and evolutionary point of view. Expand
Characterization and function of a group II type I interferon in the perciform fish, large yellow croaker (Larimichthys crocea)
TLDR
Results indicated that LcIFNc not only had antiviral activity, but also mediated the regulation of type I IFN response. Expand
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TLDR
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It is considered that IFP35 in fish is involved in antiviral, as well as in IFN-induced innate, immunity. Expand
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