Functional, morphological, and apoptotic alterations in skeletal muscle of ARC deficient mice

Abstract

Apoptotic signaling plays an important role in the development and maintenance of healthy skeletal muscle. However, dysregulation of apoptotic signals in skeletal muscle is associated with atrophy and loss of function. Apoptosis repressor with caspase recruitment domain (ARC) is a potent anti-apoptotic protein that is highly expressed in skeletal muscle… (More)
DOI: 10.1007/s10495-014-1078-9

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