Function of the sigma(E) regulon in dead-cell lysis in stationary-phase Escherichia coli.

@article{Nitta2000FunctionOT,
  title={Function of the sigma(E) regulon in dead-cell lysis in stationary-phase Escherichia coli.},
  author={Takashi Nitta and Hiroshi Nagamitsu and Makiko Murata and Hanae Izu and Masami Yamada},
  journal={Journal of bacteriology},
  year={2000},
  volume={182 18},
  pages={5231-7}
}
Elevation of active sigma(E) levels in Escherichia coli by either repressing the expression of rseA encoding an anti-sigma(E) factor or cloning rpoE in a multicopy plasmid, led to a large decrease in the number of dead cells and the accumulation of cellular proteins in the medium in the stationary phase. The numbers of CFU, however, were nearly the same as those of the wild type or cells devoid of the cloned gene. In the wild-type cells, rpoE expression was increased in the stationary phase and… CONTINUE READING

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