Function of the human T-cell leukemia virus type 1 21-base-pair repeats in basal transcription.

@article{Barnhart1997FunctionOT,
  title={Function of the human T-cell leukemia virus type 1 21-base-pair repeats in basal transcription.},
  author={Marianne Barnhart and Laurie M. Connor and Susan J. Marriott},
  journal={Journal of virology},
  year={1997},
  volume={71 1},
  pages={337-44}
}
The human T-cell leukemia virus type 1 (HTLV-1) promoter contains three copies of an imperfect 21-bp repeat called Tax-responsive element (TRE1). To examine the role of individual TRE1 sequences in basal transcription of the HTLV-1 promoter, site-directed mutations were generated in all possible combinations of one, two, or all three TRE1 elements in the viral long terminal repeat (LTR) and tested in vivo for transcriptional activity. Mutation of the middle TRE1 resulted in the greatest… CONTINUE READING
15 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

Similar Papers

Loading similar papers…