Function of heterochromatin protein 1 during DNA repair

@article{Brtov2017FunctionOH,
  title={Function of heterochromatin protein 1 during DNA repair},
  author={E. B{\'a}rtov{\'a} and Barbora Maly{\vs}kov{\'a} and D. Komůrkov{\'a} and S. Legartov{\'a} and J. Such{\'a}nkov{\'a} and J. Krej{\vc}{\'i} and S. Kozubek},
  journal={Protoplasma},
  year={2017},
  volume={254},
  pages={1233-1240}
}
  • E. Bártová, Barbora Malyšková, +4 authors S. Kozubek
  • Published 2017
  • Medicine, Biology
  • Protoplasma
  • This review focuses on the function of heterochromatin protein HP1 in response to DNA damage. We specifically outline the regulatory mechanisms in which HP1 and its interacting partners are involved. HP1 protein subtypes (HP1α, HP1β, and HP1γ) are the main components of constitutive heterochromatin, and HP1α and HP1β in particular are responsible for heterochromatin maintenance. The recruitment of these proteins to DNA lesions is also important from the perspective of proper DNA repair… CONTINUE READING
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