Function of glycosyltransferase genes involved in urdamycin A biosynthesis.

Abstract

BACKGROUND Urdamycin A, the principle product of Streptomyces fradiae Tü2717, is an angucycline-type antibiotic. The polyketide-derived aglycone moiety is glycosylated at two positions, but only limited information is available about glycosyltransferases involved in urdamycin biosynthesis. RESULTS To determine the function of three glycosyltransferase… (More)

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