Function of a principal Na(+)/H(+) antiporter, ShaA, is required for initiation of sporulation in Bacillus subtilis.

@article{Kosono2000FunctionOA,
  title={Function of a principal Na(+)/H(+) antiporter, ShaA, is required for initiation of sporulation in Bacillus subtilis.},
  author={Saori Kosono and Yoshiaki Ohashi and Fujio Kawamura and Makio Kitada and Toshiaki Kudo},
  journal={Journal of bacteriology},
  year={2000},
  volume={182 4},
  pages={898-904}
}
ShaA (sodium/hydrogen antiporter, previously termed YufT [or NtrA]), which is responsible for Na(+)/H(+) antiporter activity, is considered to be the major Na(+) excretion system in Bacillus subtilis. We found that a shaA-disrupted mutant of B. subtilis shows impaired sporulation but normal vegetative growth when the external Na(+) concentration was increased in a low range. In the shaA mutant, sigma(H)-dependent expression of spo0A (P(S)) and spoVG at an early stage of sporulation was… CONTINUE READING

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