Function of Heparin

@article{Riley1955FunctionOH,
  title={Function of Heparin},
  author={James F. Riley and D. Shepherd and Geoffrey B. West and S. W. STROUD},
  journal={Nature},
  year={1955},
  volume={176},
  pages={1123-1123}
}
BOTH heparin1 and histamine2 are now known to be concentrated in the tissue mast cells, and it might thus be expected that the release of histamine caused by damage to the mast cells would be accompanied by the release of heparin and a consequent increase in the clotting,time of blood. So far this dual effect has been observed in only one species, the dog, in which an intravenous injection of peptone or of a chemical histamine liberator such as compound 48/80 can release sufficient heparin to… CONTINUE READING

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