Function follows form: generation of intracellular signals by cell deformation.

@article{Watson1991FunctionFF,
  title={Function follows form: generation of intracellular signals by cell deformation.},
  author={Peter A. Watson},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={1991},
  volume={5 7},
  pages={2013-9}
}
  • Peter A. Watson
  • Published 1991 in
    FASEB journal : official publication of the…
Cells are exposed during their lifetimes to an array of physical forces ranging from those generated by association with other cells and extracellular matrices to the constant forces placed on cells by gravity. Alterations in these forces, either with differentiation and development or changes in activity or behavior, result in modifications in the biochemistry and adaptation in structure and function of cells. Also, a variety of differentiated cells have unique shapes that relate to extremely… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Explore Further: Topics Discussed in This Paper

Citations

Publications citing this paper.
Showing 1-10 of 81 extracted citations

Multiscale modeling of growth plate cartilage mechanobiology.

Biomechanics and modeling in mechanobiology • 2017
View 2 Excerpts

Cytoskeletal roles in cardiac ion channel expression.

Biochimica et biophysica acta • 2014
View 2 Excerpts

References

Publications referenced by this paper.
Showing 1-10 of 48 references

Fibronectin controls capillary endothelial cell growth by modulating cell shape.

Proceedings of the National Academy of Sciences of the United States of America • 1990

Ion channels and cell volume regulation : chaos in an organized system

S. A. Lewis, P. Donaldson
News PhysioL Sci . • 1990

Mechanosensitive ion channels

The Journal of Membrane Biology • 1990

Effect of cell spreading on cytoplasmic pH in normal and transformed fibroblasts.

Proceedings of the National Academy of Sciences of the United States of America • 1989

Similar Papers

Loading similar papers…