Function and ribosomal localization of aIF6, a translational regulator shared by archaea and eukarya

@inproceedings{Benelli2009FunctionAR,
  title={Function and ribosomal localization of aIF6, a translational regulator shared by archaea and eukarya},
  author={Dario Benelli and Stefano Marzi and Carmine Mancone and Tonino Alonzi and A La Teana and Paola Londei},
  booktitle={Nucleic acids research},
  year={2009}
}
The translation factor IF6 is shared by the Archaea and the Eukarya, but is not found in Bacteria. The properties of eukaryal IF6 (eIF6) have been extensively studied, but remain somewhat elusive. eIF6 behaves as a ribosome-anti-association factor and is involved in miRNA-mediated gene silencing; however, it also seems to participate in ribosome synthesis and export. Here we have determined the function and ribosomal localization of the archaeal (Sulfolobus solfataricus) IF6 homologue (aIF6… CONTINUE READING
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