Function and regulation of the pentose phosphate pathway in brain.

  title={Function and regulation of the pentose phosphate pathway in brain.},
  author={Najma Zaheer Baquer and John Stephen Hothersall and P. Mclean},
  journal={Current topics in cellular regulation},
Although the quantitative contribution of the pentose phosphate pathway to glucose metabolism in adult brain is small, numerous experiments using specific inhibitors and developmental studies (Table VI) confirm the importance and the "functional" role of this pathway in brain (for details, see reviews by Baquer et al., 1975, 1977). In this article, an attempt has been made to bring together the important findings regarding the localization, operation, and functional significance of the pentose… CONTINUE READING


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