Function and mechanism of action of Dictyostelium Nramp1 (Slc11a1) in bacterial infection.

Abstract

Dictyostelium amoebae are professional phagocytes, which ingest bacteria as the principal source of food. We have cloned the Dictyostelium homologue of human natural resistance-associated membrane protein 1 (Nramp1) [solute carrier family 11 member 1 (Slc11a1)], an endo-lysosomal membrane protein that confers on macrophages resistance to infection by a… (More)

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@article{Peracino2006FunctionAM, title={Function and mechanism of action of Dictyostelium Nramp1 (Slc11a1) in bacterial infection.}, author={Barbara Peracino and Carina Wagner and Alessandra Balest and Alessandra Balbo and Barbara Pergolizzi and Angelika A. Noegel and Michael Steinert and Salvatore Bozzaro}, journal={Traffic}, year={2006}, volume={7 1}, pages={22-38} }