Function and information content of DNA methylation


Cytosine methylation is a DNA modification generally associated with transcriptional silencing. Factors that regulate methylation have been linked to human disease, yet how they contribute to malignances remains largely unknown. Genomic maps of DNA methylation have revealed unexpected dynamics at gene regulatory regions, including active demethylation by… (More)
DOI: 10.1038/nature14192

4 Figures and Tables


  • Presentations referencing similar topics