Function and evolution of a MicroRNA that regulates a Ca2+-ATPase and triggers the formation of phased small interfering RNAs in tomato reproductive growth.

@article{Wang2011FunctionAE,
  title={Function and evolution of a MicroRNA that regulates a Ca2+-ATPase and triggers the formation of phased small interfering RNAs in tomato reproductive growth.},
  author={Ying Wang and Asuka Itaya and Xuehua Zhong and Yang Wu and Jianfeng Zhang and Esther van der Knaap and Richard Olmstead and Yijun Qi and Biao Ding},
  journal={The Plant cell},
  year={2011},
  volume={23 9},
  pages={3185-203}
}
MicroRNAs (miRNAs) regulate a wide variety of biological processes in most eukaryotes. We investigated the function and evolution of miR4376 in the family Solanaceae. We report that the 22-nucleotide miR4376 regulates the expression of an autoinhibited Ca(2+)-ATPase, tomato (Solanum lycopersicum) ACA10, which plays a critical role in tomato reproductive growth. Deep phylogenetic mapping suggested (1) an evolution course of MIR4376 loci and posttranscriptional processing of pre-miR4376 as a… CONTINUE READING