Function and distribution of beta3-adrenoceptors in rat, rabbit and human urinary bladder and external urethral sphincter.

@article{Morita2000FunctionAD,
  title={Function and distribution of beta3-adrenoceptors in rat, rabbit and human urinary bladder and external urethral sphincter.},
  author={Takayuki Morita and Hiroyuki Iizuka and Takeshi Iwata and Shigemi Kondo},
  journal={Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi},
  year={2000},
  volume={36 1},
  pages={21-32}
}
1. Activation of beta-adrenoceptors causes relaxation of the urinary bladder and contraction of the external urethral sphincter, which consists of fast-contracting skeletal muscles. A beta2-adrenoceptor agonist, clenbuterol, recently has been developed as a therapeutic drug for the treatment of urinary incontinence, however beta2-adrenoceptor agonists have undesirable effects on cardiac and striated muscle function. 2. In this study, we compared the effects of the beta2-adrenoceptor agonist… CONTINUE READING

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