Fumagillin, a Mycotoxin of Aspergillus fumigatus: Biosynthesis, Biological Activities, Detection, and Applications

@article{Guruceaga2019FumagillinAM,
  title={Fumagillin, a Mycotoxin of Aspergillus fumigatus: Biosynthesis, Biological Activities, Detection, and Applications},
  author={Xabier Guruceaga and Uxue Perez-Cuesta and Ana Abad-Diaz de Cerio and Oskar Gonz{\'a}lez and Rosa Mar{\'i}a Alonso and Fernando Luis Hernando and Andoni Ramirez-Garcia and Aitor Rementeria},
  journal={Toxins},
  year={2019},
  volume={12}
}
Fumagillin is a mycotoxin produced, above all, by the saprophytic filamentous fungus Aspergillus fumigatus. This mold is an opportunistic pathogen that can cause invasive aspergillosis, a disease that has high mortality rates linked to it. Its ability to adapt to environmental stresses through the production of secondary metabolites, including several mycotoxins (gliotoxin, fumagillin, pseurotin A, etc.) also seem to play an important role in causing these infections. Since the discovery of the… Expand
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