[Fulminating hepatitis A in children. Apropos of 4 cases].


We report four cases of fulminant hepatitis in children (4 to 15 years) who developed an hepatic encephalopathy grade III to IV, 4 to 13 days after the onset of their illness. Three patients recovered without sequelae. The complications were neurological: one child showed elevation of the intracranial pressure, successfully treated after monitoring of extra-dural pressure; one suffered from cerebral death. Hepatitis A was diagnosed by the presence in serum of the IgM component of hepatitis A antibody, but another etiologic factor was present in two cases: an halothane anesthesia and an Epstein Barr virus infection which could explain the severity of the hepatitis.

Cite this paper

@article{Rayet1987FulminatingHA, title={[Fulminating hepatitis A in children. Apropos of 4 cases].}, author={Isabelle Rayet and Georges Teyssier and Gilles Damon and Didier Frappaz and A Colmant and Bruno Pozzetto}, journal={Pédiatrie}, year={1987}, volume={42 1}, pages={37-40} }