Fulminant Myocarditis: Epidemiology, Pathogenesis, Diagnosis, and Management.

@article{Sharma2019FulminantME,
  title={Fulminant Myocarditis: Epidemiology, Pathogenesis, Diagnosis, and Management.},
  author={Ajay Nair Sharma and Jacob Stultz and Nikhil Bellamkonda and Ezra A. Amsterdam},
  journal={The American journal of cardiology},
  year={2019}
}
Fulminant Myocarditis: Brief Review
TLDR
Patients with FM are more likely to die or need heart transplantation than those with the nonfulminant form of the disease, and early recognition and aggressive management are essential for favorable outcomes.
Fulminant myocarditis: a comprehensive review from etiology to treatments and outcomes
TLDR
This review provides a comprehensive account of the current understanding of FM pathophysiology and knowledge regarding its etiology, pathophysiological, treatments, and outcomes.
Fulminant Giant Cell Myocarditis vs. Lymphocytic Myocarditis: A Comparison of Their Clinical Characteristics, Treatments, and Outcomes
TLDR
The results suggest that hs-CRP could be a promising prognostic biomarker and a hs -CRP level of 11.71 mg/L is an appropriate cutoff point for the differentiating diagnosis between patients with FGCM and FLM.
Fulminant myocarditis with myositis of ocular and respiratory muscles
TLDR
A 46-year-old Japanese woman visited a nearby hospital because of diplopia after flu-like symptoms and presented with blepharoptosis and external ophthalmoplegia, resulting in a diagnosis of acute myocarditis, and underwent intravenous immunoglobulin therapy and rehabilitation.
Influenza-associated Fulminant Myocarditis Complicated by Guillain-Barré Syndrome
TLDR
The case of a 47-year-old woman who was admitted with weakness and numbness of the limbs and dyspnea after being infected with influenza virus A and diagnosed with fulminant myocarditis, which was complicated by GBS is reported.
Establishment and assessment of a nomogram model for predicting the risk of fulminant myocarditis
TLDR
The contribution of the 6 significant factors to predicting fulminant myocarditis risk was significant from multi-angle analyses, and regressing these factors in a nomogram model exhibited good predictive accuracy, as reflected by both C-index and P-index.
Characterization and long-term outcomes of patients with myocarditis: a retrospective observational study
TLDR
The overall prognosis of patients with myocarditis is good – in terms of both survival and recovery without residual left ventricular dysfunction.
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TLDR
The most clinically relevant observation was that fulminant myocarditis patients, although much more ill at presentation had an improved chance of full recovery and long-term survival.
Long-term outcome of fulminant myocarditis as compared with acute (nonfulminant) myocarditis.
TLDR
Fulminant myocarditis is a distinct clinical entity with an excellent long-term prognosis and Aggressive hemodynamic support is warranted for patients with this condition.
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From a functional viewpoint, patients with FM have a more severely impaired LVEF at admission that, despite steep improvement during hospitalization, remains lower than that in patients with NFM at long-term follow-up, which holds true when only the viral forms are considered.
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Overall serious adverse events after AM were lower than previously reported, however, patients with left ventricular ejection fraction <50%, ventricular arrhythmias, or low cardiac output syndrome at presentation were at higher risk compared with uncomplicated cases that had a benign prognosis and low risk of subsequentleft ventricular systolic dysfunction.
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TLDR
In myocarditis, biventricular dysfunction at diagnosis was the main predictor of death/transplantation and AHA identified immune-mediatedMyocarditis in the majority of cases, and viral genome was a univariate predictor of adverse prognosis.
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