Fully automated ultrasensitive digital immunoassay for cardiac troponin I based on single molecule array technology.

@article{Jarolim2015FullyAU,
  title={Fully automated ultrasensitive digital immunoassay for cardiac troponin I based on single molecule array technology.},
  author={Petr Jarolim and Purvish P. Patel and Michael Conrad and Lei Chang and Vojtech Melenovsky and David Henry Wilson},
  journal={Clinical chemistry},
  year={2015},
  volume={61 10},
  pages={
          1283-91
        }
}
BACKGROUND The association between increases in cardiac troponin and adverse cardiac outcomes is well established. There is a growing interest in exploring routine cardiac troponin monitoring as a potential early indicator of adverse heart health trends. Prognostic use of cardiac troponin measurements requires an assay with very high sensitivity and outstanding analytical performance. We report development and preliminary validation of an investigational assay meeting these requirements and… CONTINUE READING

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