Full Steam Ahead--Probably

@article{Lorenz2003FullSA,
  title={Full Steam Ahead--Probably},
  author={Ralph D. Lorenz},
  journal={Science},
  year={2003},
  volume={299},
  pages={837 - 838}
}
  • R. Lorenz
  • Published 7 February 2003
  • Physics
  • Science
It has long been argued that complex systems like Earth's climate may be in a state of maximum entropy production. In such a state, the work output-or, crudely, the product of the heat flux and the temperature gradient driving it-is maximized. But, as [Lorenz][1] explains in his Perspective, no reason for why systems should choose this state has been known. He highlights a recent paper that shows how the maximum entropy production state can become the most probable state. [1]: http://www… 
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疟原虫var基因转换速率变化导致抗原变异[英]/Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A
抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1(PfPMP1)与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用,在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员,通过启动转录不同的var基因变异体为抗原变异提供了分子基础。
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