Full Peptide Synthesis, Purification, and Characterization of Six Tat Variants

@article{Ploponse1999FullPS,
  title={Full Peptide Synthesis, Purification, and Characterization of Six Tat Variants},
  author={J. P{\'e}lopon{\`e}se and Y. Collette and C. Grégoire and C. Bailly and D. Campèse and E. Meurs and D. Olive and E. Loret},
  journal={The Journal of Biological Chemistry},
  year={1999},
  volume={274},
  pages={11473 - 11478}
}
AIDS in Africa is characterized by the equal distribution of mortality between the two genders because of highly virulent human immunodeficiency virus type 1 (HIV-1) strains. The viral protein Tat trans-activates viral gene expression and is essential for HIV-1 replication. We chemically synthesized six different Tat proteins, with sizes ranging from 86 to 101 residues, from HIV-1 isolates located in different parts of the world including highly virulent African strains. Protein purification… Expand
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TLDR
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TLDR
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