Full-Genome Characterisation of Orungo, Lebombo and Changuinola Viruses Provides Evidence for Co-Evolution of Orbiviruses with Their Arthropod Vectors

@article{Jaafar2014FullGenomeCO,
  title={Full-Genome Characterisation of Orungo, Lebombo and Changuinola Viruses Provides Evidence for Co-Evolution of Orbiviruses with Their Arthropod Vectors},
  author={F. Mohd Jaafar and Mourad Belhouchet and M. Belaganahalli and R. Tesh and Peter P. C. Mertens and H. Attoui},
  journal={PLoS ONE},
  year={2014},
  volume={9}
}
  • F. Mohd Jaafar, Mourad Belhouchet, +3 authors H. Attoui
  • Published 2014
  • Biology, Medicine
  • PLoS ONE
  • The complete genomes of Orungo virus (ORUV), Lebombo virus (LEBV) and Changuinola virus (CGLV) were sequenced, confirming that they each encode 11 distinct proteins (VP1-VP7 and NS1-NS4). Phylogenetic analyses of cell-attachment protein ‘outer-capsid protein 1′ (OC1), show that orbiviruses fall into three large groups, identified as: VP2(OC1), in which OC1 is the 2nd largest protein, including the Culicoides transmitted orbiviruses; VP3(OC1), which includes the mosquito transmitted orbiviruses… CONTINUE READING
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