Fucosylation and galactosylation of IgG heavy chains differ between acute and remission phases of juvenile chronic arthritis.

@article{Flgel1998FucosylationAG,
  title={Fucosylation and galactosylation of IgG heavy chains differ between acute and remission phases of juvenile chronic arthritis.},
  author={Mirna Fl{\"o}gel and Gordan Lauc and Ivan Gornik and Boris Ma{\vc}ek},
  journal={Clinical chemistry and laboratory medicine},
  year={1998},
  volume={36 2},
  pages={99-102}
}
Oligosaccharide structures are attached to nearly all membrane and serum proteins, and their composition changes significantly in many diseases. We have analysed glycosylation of IgG heavy chains in 34 patients with juvenile chronic arthritis and 13 control individuals. IgG was purified from 0.7 ml of serum, separated by electrophoresis and transferred on to polyvinylidene difluoride (PVDF) membrane. Ricinus communis agglutinin (RCA I) and Bandeirea simplicifolia (BSA II) and Ulex europaeus… CONTINUE READING