Fucosylated surfactant protein-D is a biomarker candidate for the development of chronic obstructive pulmonary disease.

@article{Ito2015FucosylatedSP,
  title={Fucosylated surfactant protein-D is a biomarker candidate for the development of chronic obstructive pulmonary disease.},
  author={Emi Ito and Ritsuko Oka and T. Koryu Ishii and Hiroaki Korekane and Ayako Kurimoto and Yasuhiko Kizuka and Shinobu Kitazume and Shigeru Ariki and Motoko Takahashi and Yoshio Kuroki and Kozui Kida and Naoyuki Taniguchi},
  journal={Journal of proteomics},
  year={2015},
  volume={127 Pt B},
  pages={386-94}
}
UNLABELLED We previously reported that knockout mice for α1,6-fucosyltransferase (Fut8), which catalyzes the biosynthesis of core-fucose in N-glycans, develop emphysema and that Fut8 heterozygous knockout mice are more sensitive to cigarette smoke-induced emphysema than wild-type mice. Moreover, a lower FUT8 activity was found to be associated with a faster decline in lung function among chronic obstructive pulmonary disease (COPD) patients. These results led us to hypothesize that core… CONTINUE READING
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Surfactant protein D in chronic obstructive pulmonary disease (COPD)

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  • 2014
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