Fucoidan present in brown algae induces apoptosis of human colon cancer cells

@inproceedings{Kim2010FucoidanPI,
  title={Fucoidan present in brown algae induces apoptosis of human colon cancer cells},
  author={Eun Ji Kim and So Young Park and Jae-young Lee and Jung Han Yoon Park},
  booktitle={BMC gastroenterology},
  year={2010}
}
BACKGROUND Fucoidan is a sulfated polysaccharide found in brown algae; it has been shown to exhibit a number of biological effects, including anti-tumor effects. In this study, we evaluated the effects of fucoidan on apoptosis in HT-29 and HCT116 human colon cancer cells. METHODS HT-29 and HCT116 cells were cultured with various concentrations of fucoidan (0 - 20 microg/mL). Apoptosis was assayed via Hoechst staining and Annexin V staining followed by flow cytometric analysis. Western blot… CONTINUE READING