Fucoidan extract derived from Undaria pinnatifida inhibits angiogenesis by human umbilical vein endothelial cells.

@article{Liu2012FucoidanED,
  title={Fucoidan extract derived from Undaria pinnatifida inhibits angiogenesis by human umbilical vein endothelial cells.},
  author={Fang Liu and Jia Wang and Alan Kuei-Chieh Chang and Bing Liu and Lili Yang and Qiaomei Li and Peisheng Wang and Xiangyang Zou},
  journal={Phytomedicine : international journal of phytotherapy and phytopharmacology},
  year={2012},
  volume={19 8-9},
  pages={797-803}
}
In recent years, anti-angiogenic therapy has become an effective strategy for inhibiting tumor growth. Fucoidan is a class of fucose-enriched sulfated polysaccharides found in brown algae, and it is known to have strong anti-tumor property. Using a human umbilical vein endothelial cells (HUVEC)-based cell culture model, the present study investigated the anti-angiogenic activity of fucoidan extracted from the brown seaweed Undaria pinnatifida. Treatment of HUVECs with various concentrations of… CONTINUE READING
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